Rare Disease Diagnosis
The knowledge exists, but the route from symptom pattern to possible diagnosis is still too slow.
Built — prototype matching can help, but clinical trust is the work.
Avenues
Nine domains where the technology is ready and deployment is not. Each is a problem I looked at long enough to draw a map of; some produced tools, some essays, some are still notes.
The frame is in Working Theory.
Consumer Rights
EU protections are strong on paper; enforcement often depends on whether a person can bear the friction.
Built — document the right, then lower the cost of using it.
Pharmacogenomics
Many people already hold genetic data that could change prescriptions. The clinical path is the hard part.
Tractable — interpretation is easy; responsibility is not.
Desalination
Water technology can work beautifully and still fail in procurement, maintenance, and local trust.
Mapped — the failures are operational before they are technical.
Landfill Robotics
AI sorting and urban mining sound ready, but the business case collapses once contaminated fines, liability, and land value enter the picture.
Mapped — the robot is not the bottleneck; the dirt and liability are.
Retrofit
Homes need better energy decisions than a generic checklist can provide, especially when subsidies are involved.
Built — advice has to meet the house, the bill, and the subsidy.
Soil
The living layer under everything is measurable, neglected, and harder to restore than to damage.
Mapped — useful if it reaches the farmer, not just the dataset.
Hearing Aids
A small device can change a life, but stigma, price, and fitting workflows keep help out of reach.
Tractable — access is social, clinical, and commercial at once.
Household Risk
Radon and other quiet risks sit between public health, housing data, and ordinary domestic uncertainty.
Built — local risk needs a clear next action, not ambient dread.